Rodent models of inflammatory pain have been widely used to study the mechanisms of tissue injury-induced persistent pain. A number of different irritants have been utilized to induce skin, paw, muscle, joint, and visceral organs to produce tissue injury and hyperalgesia. Alpha has many years of experience with inflammation models, we can perform comprehensive evaluations of your anti-inflammatory compounds.

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Key models include:

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• Complete Freund's Adjuvant (CFA)-induced osteoarthritis

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• Bleomycin induced pulmonary fibrosis

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• LPS-induced inflammation

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