In vivo tumor induction models promote a state of sustained proliferation, hyperplasia, chronic inflammation, and oxidative stress. Alpha uses various commercially available murine and human cell lines to create:

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• Subcutaneous tumor models for PD target anti-tumor activity dose response evaluations

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• Orthotopic tumor models evaluate tumor progression

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• In life and ex vivo Spectrum IVIS bioluminescence (luciferase activated) imaging