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Metabolic Diseases

PK/PD

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Gene Therapy

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Autoimmune Disease

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Metabolic Diseases 

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Inflammation/ Fibrosis Models

Tumor Models

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Metabolic disease and disorders disrupt normal homeostasis affecting the ability of the organ/cell to perform critical biochemical functions that involve the processing or transport of proteins, carbohydrates, or lipids. With many years of experience and access to scientific leaders in the diabetic field, Alpha can perform comprehensive evaluations of your metabolic compounds.

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Key models include:

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  • Obesity: diet-induced obesity (DIO) rodents and ob/ob mice

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  • Type 2 diabetes: db/db mice and ZDF rats

    • Wound healing

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  • Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) 

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  • High fat diet induced dyslipidemia/hypercholesterolemia

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